Fabio Urbina’s stellar work, defining exocytic modes, their regulatory mechanisms, and their influence on cell morphology is out in Cell Reports.
Category Archives: Lab Members
The TRIM9/TRIM67 Interactome
Shalini Menon published a first author paper in Molecular Biology of the Cell detailing the interactome of TRIM9 and TRIM67 using the BioID approach. Shalini led a team of undergrads to complete this work in collaboration with the Major Lab.
Shalini Menon publishes the neuronal ubiquitylome
We took our first foray into getting data out there at µPublications. Shalini used proteomic approaches to define the ubiquitylome of developing neurons. Although we didn’t have the power to detect differences between genotypes, we think this data will be useful to many labs. Please let us know if your favorite protein is ubiquitylated.
Juliet King Rotates in the lab
Welcome Juliet King for the second BBSP rotation.
Congratulations and Best Wishes to Shalini Menon
Shalini Menon, PhD has accepted a position at KBI Pharmaceuticals as Scientist 1. Congratulations Shalini! We will miss you.
the TRIM9/TRIM67 Interactome
New Preprint from the lab by Shalini Menon et al is available on BioRxiv. “The TRIM9/TRIM67 neuronal interactome reveals novel activators of morphogenesis”
Gupton Lab Works Remotely
The Gupton lab started ramping down our lab work the second week of March, and shuttered our doors on March 17th to socially isolate and slow the spread of coronavirus. We donated all our available PPE and while we miss the lab, we are happy to do our small part in this battle. We have plenty of writing and data analysis to do at home. See you soon lab!
Laura will head to MBL Physiology Course!
Laura McCormick was accepted into the historic Physiology course at the Marine Biological Laboratories in Woods Hole MA. Congrats Laura!
Two New Internal Funding Awards
Laura McCormick received a 10k CFAC award for her proposal to define proteome changes in the PSD of our Trim9 and Trim67 knockout mice! Stephanie Gupton and Saskia Neher received a 50K award to study LPL trafficking from the School of Medicine Emerging Challenges in Biological Research
New lab preprint on TRIM67, SNAP47 and exocytic mode
Fabio Urbina et al., post a preprint on BioRxiv showing SNARE complex composition distinguishes discrete modes of exocytosis with distinct kinetics and diverse consequences in membrane addition and morphogenesis in developing cortical neurons.