Anigika Basant highlighted a preprint from the lab on PreLights. This nicely highlights the significance of the work and summarizes our major findings.
Category Archives: Publications!
TRIMing Neural connections with Ubiquitin
Denise Montell highlighted Nick’s eNeuro publication of the role of TRIM67 in Brain Development in a great SpotLight in Developmental Cell. Thank you Denise!
Recent advances in branching mechanisms underlying neuronal morphogenesis
Shalini Menon publishes a first author commentary of Recent advances in branching mechanisms underlying neuronal morphogenesis in F1000 Research.
TRIM9 and TRIM67 are new targets in paraneoplastic cerebellar degeneration
A fun and fruitful collaborative study with the lab of Le Duy Do and Jerome Honnorat at the University of Lyon, France is now in press in Cerebellum.
Nick and Stephanie publish a review of 25 years of netrin.
- Nick Boyer and Stephanie publish a review: Netrin-1, the one who guides axons, in Frontiers in Cellular Neuroscience.
Mammalian TRIM67 functions in brain development and behavior
Check out the consequences of genetic deletion of Trim67.
Deletion of murine Trim67 results in malformations of a subset of subcortical brain regions and of cortical and subcortical myelinated fiber tracts, as well as deficits in spatial memory, motor function, sociability and sensorimotor gating. Interactions between TRIM67 and both the netrin receptor DCC and TRIM9, and abnormalities in netrin-sensitive brain regions are noted. We conclude that TRIM67 is critical for appropriate brain development and behavior.
http://www.eneuro.org/content/early/2018/05/29/ENEURO.0186-18.2018