The lab received a notice of award for some new work investigating glycosylation of the axon guidance cue Netrin from the Mizutani Foundation for Glycoscience!
All posts by Stephanie Gupton
TRIMing Neural connections with Ubiquitin
Denise Montell highlighted Nick’s eNeuro publication of the role of TRIM67 in Brain Development in a great SpotLight in Developmental Cell. Thank you Denise!
Recent advances in branching mechanisms underlying neuronal morphogenesis
Shalini Menon publishes a first author commentary of Recent advances in branching mechanisms underlying neuronal morphogenesis in F1000 Research.
Stephanie attends Scialog, chemical machinary of the cell
Stephanie spent a few thoughtful days in the high desert of Tucson discussing the Chemical Machinery of the Cell, a Scialog event hosted by the Research Corporation for Science Advancement.
TRIM9 and TRIM67 are new targets in paraneoplastic cerebellar degeneration
A fun and fruitful collaborative study with the lab of Le Duy Do and Jerome Honnorat at the University of Lyon, France is now in press in Cerebellum.
Emily Wolfgram attends SACNAS
Emily Wolfgram attended the annual SACNAS conference ( Society for Advancement of Chicanos/Hispanics and Native Americans in Science) in San Antonio, TX where she won an award for undergraduate poster presentation in the field of Cell/Molecular Biology. Congratulations Emily.
Melissa Plooster gets an F31 NRSA from NIMH
Congratulations to Melissa Plooster, for earning a well deserved F31 from the NIH/National Institute of Mental Health for her thesis work on tSNARE1.
Nick and Stephanie publish a review of 25 years of netrin.
- Nick Boyer and Stephanie publish a review: Netrin-1, the one who guides axons, in Frontiers in Cellular Neuroscience.
Fabio Urbina heads to the MBL for the Physiology Course
Fabio wil be spending seven weeks in Woods Hole, MA at the historic Physiology Course at the Marine Biological Laboratories.
Mammalian TRIM67 functions in brain development and behavior
Check out the consequences of genetic deletion of Trim67.
Deletion of murine Trim67 results in malformations of a subset of subcortical brain regions and of cortical and subcortical myelinated fiber tracts, as well as deficits in spatial memory, motor function, sociability and sensorimotor gating. Interactions between TRIM67 and both the netrin receptor DCC and TRIM9, and abnormalities in netrin-sensitive brain regions are noted. We conclude that TRIM67 is critical for appropriate brain development and behavior.
http://www.eneuro.org/content/early/2018/05/29/ENEURO.0186-18.2018